Consistently, we found a significantly positive correlation between the protein abundance of SHC1 and the TGFβ signaling pathway enrichment score (Pearson’s correlation, r = 0.15, p value = 0.028), suggesting an association between SHC1 and the TGFβ signaling in sarcoma (Fig. 2E). This evidence concerns the gene TGFB1 and sarcoma.