To test the clinical relevance of SHC1 targeting for HC1 (AS and ES), we collected 6 different sarcoma cell lines, including 2 AS cell lines (ISO-HAS and ASM), 2 ES cell lines (VA-ES-BJ and SU-CCS-1), and 2 WDLPS cell lines (93T449 and SW-872). The gene discussed is SHC1; the disease is sarcoma.