We also evaluated the expression of reported diagnostic markers across various subtypes, including CDK4 (a marker for WDLPS), CDKN2A (a marker for DDLPS), S100B (a marker for MPNST), TLE1 (a marker for SS), DES (a marker for LMS), and others35–40 (Fig. 1E, Supplementary Fig. 6A–C). This evidence concerns the gene S100B and dedifferentiated liposarcoma.