IGHE and chronic rhinosinusitis with nasal polyps: In addition, although the treatment of patients with CRSwNP is very confusing and different treatments have distinct effects on patients, anti-IgE therapeutic strategies such as omalizumab are effective and quick-acting because they prevent the overproduction of PGs and cysteinyl LTs in addition to functioning as a mast cell stabilizer for patients with AERD [27].