Epilepsy is a hallmark feature of STXBP1 encephalopathy, and patients present diverse seizure types including epileptic spasm, focal, tonic, clonic, myoclonic, and absence seizures (Stamberger et al., 2016; Suri et al., 2017). This evidence concerns the gene STXBP1 and Generalized non-motor (absence) seizure.