Furthermore, Stxbp1 haploinsufficiency in Pv, Sst, or Htr3a neurons alone did not cause epilepsy, which suggests that the myoclonic seizures in Viaat-cHet mice result from the collective action of either more than one specific type of GABAergic/glycinergic neurons or simply >30–40% of GABAergic/glycinergic neurons regardless the type. The gene discussed is HTR3A; the disease is epilepsy.