We next evaluated motor functions using vertical pole, foot slip tests, and rotarod, as motor deficits are prevalent in STXBP1 encephalopathy patients (Stamberger et al., 2016; Xian et al., 2022) and were observed in Stxbp1tm1d/+ and Stxbp1tm1a/+ mice (Chen et al., 2020). The gene discussed is STXBP1; the disease is Encephalopathy.