It should be noticed that a study performed in SCC (Squamous Cell Carcinoma) and aimed at determining the nuclear receptors, which are involved in the regulation of CAF functionality, resulted in the identification of RARβ, PPARβ-δ, VDR (Vitamin D Receptor), GR (Glucocorticoid Receptor) and AR (Androgen Receptor) as key players in the attenuation of the invasiveness, proliferation, drug resistance, energy metabolism and oxidative stress observed in the neoplastic cell. This evidence concerns the gene AR and squamous cell carcinoma.