PDPN and breast neoplasm: According to Niemiec et al., PDPN+ CAFs isolated from HER2-overexpressing breast carcinomas facilitate the migration of breast tumor cells [81], but Suchanski et al. described that PDPN expressed on the surface of human fibroblastic cell lines (MSU1.1 and Hs 578Bst) does not change the migration rate of cells that were also used in these studies—MCF-7 and MDA-MB-23 [82].