CDH1 and breast carcinoma: In both breast cancer cell lines, MCF-7 and MDA-MB-231, CM from calcitriol-treated CAFs from premenopausal women’s tumors decreased the level of E-cadherin, while CM from CAFs from postmenopausal patients did not change the E-cadherin level (Fig. 10A1, A4, B1 and B4).