Sequencing data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEX) were analyzed using the Gene Expression Profiling Interactive Analysis (GEPIA2) platform, and the results showed that GRP78 levels were increased in multiple tumors, including colon cancer (Additional file 1: Fig. S4E). This evidence concerns the gene HSPA5 and malignant colon neoplasm.