In the malaria-infected samples, a subset of ICD genes, such as TNF, P2RX7,BAX, IFNG, PRF1, CALR, HSP90AA1, IL6, IFNGR1, IL17RA, ENTPD1, MYD88, CASP1, IL1B, LY96 and TLR4, exhibited significant upregulation. Here, IL1B is linked to malaria.