Using data from the UK Biobank, we conducted a phenome wide association study with each APOL1 genotype in turn and have demonstrated that no association was detected when grouping G1/G1, G1/G2 and G2/G2 risk genotypes together, however, when each genotype was examined individually, a spectrum of 27 potential APOL1-associated conditions was detected in addition to kidney disease. This evidence concerns the gene APOL1 and kidney disorder.