For example, iPSC-CMs were generated from five DCM patients harboring pathogenic mutations in titin (TTN, c.73817delC, p.P24606LfsX16), phospholamban (PLN, c.40_42delAGA, p.R14del), lamin A/C (LMNA, c.967_968delCT, p.L323fs), tropomyosin 1 (TPM1, c.688G>A, p.D230N), and laminin subunit alpha 2 (LAMA2, c.7074C>A, p.Y2358X). Here, LMNA is linked to familial dilated cardiomyopathy.