PIK3C2A and cystic fibrosis: CF rabbits, in comparison with WT rabbits, had many abnormal BCPs, which included lower levels of potassium (K+), higher levels of triglyceride and cholesterol, elevated alanine aminotransferase (ALT), alkaline phosphatase (ALP), and creatine phosphokinase (CPK), and decreased total protein (TPRO) concentrations (Figure 3 and Supplemental Figure 3).