S100A8 and neoplasm: Neutrophils sorted from the livers of villin-CreERT2KrasG12D/+ Trp53fl/flRosa26N1icd/+ (KPN) tumor-bearing mice 28 days following intrasplenic injection of Mrp8-Cre-Cxcr2fl/fl (Mrp8CreYCxcr2Δneut) or Mrp8-Cre-negative-Cxcr2fl/fl (Mrp8CreN) backgrounds showed significant suppression of T-cell proliferation in the Cxcr2fl/fl setting comparable with WT neutrophils (Fig. 5B–D).