To determine whether the response to alisertib was MAVS dependent in colorectal cancer cells, we made CRISPR KOs of MAVS or STING in HT-29, CT26, Ls174T, and SW1417 cell lines (Supplementary Table S6) and assayed for IFN pathway induction in response to AURKis. The gene discussed is STING1; the disease is colorectal cancer.