Studies have determined a relationship between ANXA1 and vascular degeneration in which ANXA1 can suppress inflammation by inhibiting dihydronicotinamide adenine dinuclectide phosphate oxidases in endothelial cells.[31] In addition, ANXA1 expression is decreased in HUVECs with acute‐induced inflammation.[32] Of importance for microvascular diseases, ANXA1 expression is also decreased in cerebral blood vessels during hypoxia‐ischemia,[18, 33] suggesting that ANXA1 might be linked to vascular disorders and, if possible, could be able to postpone vascular aging. Here, ANXA1 is linked to vascular disorder.