To ascertain the collagen types produced by CAFs, scRNA-Seq data from our pediatric glioma cohort complemented with public adult glioblastoma data sets (5) were analyzed and showed that CAFs expressed COL6A1/A2 > COL4A1, COL9A3, COL12A1 > COL1A (Figure 1E and Supplemental Figure 1A; supplemental material available online with this article; https://doi.org/10.1172/JCI176613DS1). Here, COL6A1 is linked to central nervous system cancer.