By using the IVW method, we found that higher levels of IL-4 and IL-1RA genetic prediction were associated with a lower risk of atopic dermatitis, OR = 0.878, 95% CI = 0.78–0.99, p = 0.036 per 1 standard deviation (SD); OR = 0.902, 95% CI = 0.82–1.00, p = 0.045 per 1 standard deviation (SD) (Figures 3A,B,E,F). The gene discussed is IL4; the disease is atopic eczema.