TNF and coronary artery disorder: ROC curve analysis was carried out on MMP-9 gene expression, MMP-9 and TNF-α levels, which revealed these factors had a high discriminatory power for detecting CAD.ROC analysis revealed the following Area under curve (AUC) for the MMP-9 gene, MMP-9 and TNF-α levels (AUC = 0.763, 95% CI: 0.682, 0.845, AUC = 0.863, 95% CI: 0.792, 0.934, 0.707, 95% CI: 0.618, 0.796; all P value = 0.001, respectively) (Figure 5).