The analysis of this network reveals that CD8A, CD68, and VISTA can be significantly influenced by critical proteins and transcription factors such as TP53, EP300, ESR1, CCND1, CREBBP, FOS, HDAC1, SMAD3, SMAD2, and STAT1, thereby having a role in cancer tumorigenesis. The gene discussed is CCND1; the disease is cancer.