Furthermore, Sacreas et al [19] suggested that the fibrotic process of RAS mirrors that of idiopathic pulmonary fibrosis and may be driven by mesothelial-to-mesenchymal transition, characterized by differentiation of pleural mesothelial cells into myofibroblasts after stimulation by TGFβ. The gene discussed is TGFB1; the disease is pulmonary fibrosis.