The etiology, degree of varicose veins, bleeding location, presence or absence of co-infection, ascites, portal vein thrombosis or tumor thrombus, albumin, platelets, prothrombin activity, Child Pugh classification, the proportion of Child Pugh classification C in the TIPS hemostasis failure group was higher than that in the successful hemostasis group, and the activities of albumin and prothrombin were lower than those in the successful hemostasis group, P<0.05, and the differences were statistically significant (Table 4). The gene discussed is F2; the disease is Portal vein thrombosis.