The Compound Phylanthus urinaria II has been shown to inhibit HepG2 cell proliferation by modulating the ceRNA network lncRNA CCAT1/miR-let-7a/HMGA2/Cyclin D1 axis, thereby enhancing the inhibitory effect of miR-let-7a on HMGA2 and Cyclin D1 expression, manifesting its anti-HCC properties (Chen et al., 2021b). The gene discussed is CCND1; the disease is hepatocellular carcinoma.