Similarly, hypoalbuminemia is linked to tumor progression and poor survival in lung cancer.9,57 Furthermore, it has been observed that as CRP levels increase, albumin levels tend to decline in cancer patients, suggesting a connection between systemic inflammation and cachexia.58 It was shown in a recent study by Ran et al. (2022) that a number of factors affect the prognosis and survival of elderly patients with advanced NSCLC.59 Age, performance status score, smoking history, and style of treatment are some of these variables. This evidence concerns the gene ALB and Hypoalbuminemia.