ACE and hypertensive disorder: In control out of 60 only four (6.66%) were DD and 25 (41.66%) were II genotype while other Pakistani study showed that DD genotype of ACE gene was 28.8%.21 Study on Punjabi Population of Pakistan showed that ACE ID polymorphism have association with hypertension (OR: 2.844: CI: 1.32–6.110).