ACE and hypertensive disorder: Essential HTN is a multifactorial disorder caused by genetic, demographic and environmental factors.14 Renin Angiotensin Aldosterone System (RAAS) gene polymorphisms have been studied in different ethnic groups to find the genetic susceptibility to HTN.15 There is 287 bp insertion or deletion of ACE gene in the 16th Intron of chromosome number 17 which result increased plasma and serum ACE level.