ACE and hypertensive disorder: About 50 to 60% of patients are sensitive to salt due to genetics and there is chance to develop essential hypertension.6 It is estimated that 30-50% of hypertension is due to genetics and up to now only 2-3% of polymorphism has been found.7 Among various genes polymorphisms ACE gene have association with hypertension.8 Angiotensinogen is the precursor of angiotensin and its production occur in the liver.