In CRC patients, TET2 expression showed a negative correlation with M0 macrophages (Spearman's r = -0.530, p = 0.004) and activated mast cells (Spearman's r = -0.432, p = 0.022) but was positively associated with resting mast cells (Spearman's r = 0.382, p = 0.045) (Figure 5H-5J). This evidence concerns the gene TET2 and colorectal carcinoma.