We conducted an in-depth study using the TCGA Pan-Cancer data downloaded from UCSC and found that NFIL3 mutated in 9 types of cancers, including CESC (WT = 283, Mut = 3), COAD (WT = 277, Mut = 5), COADREAD (WT = 366, Mut = 5), BRCA (WT = 976, Mut = 4), STES (WT = 583, Mut = 6), STAD (WT = 403, Mut = 6), UCEC (WT = 171, Mut = 4), LUSC (WT = 482, Mut = 3), OV (WT = 300, Mut = 3) (Figure 4A). The gene discussed is NFIL3; the disease is polyarteritis nodosa.