ALDOA and osteosarcoma: For example, LncRNA BE503655 inhibits proliferation, invasion, and migration of osteosarcoma through the Wnt/β-catenin pathway 17, whereas Shen et al. 10 discovered that lncRNA KCNQ1OT1 sponges miR-34c-5p and promotes osteosarcoma development by enhancing aerobic glycolysis through ALDOA.