A total of 31 tissue-gene pairs were observed for T2DM and GSD, including 16 genes (DMWD, GPN1, GTF3C2, IFT172, KRTCAP3, LINC01126, LINC01460, NRBP1, OASL, P2RX4, PPM1G, RBKS, SPPL3, SNX17, THADA, UNC119B), mainly expressed in multiple tissues from nervous and motor systems. This evidence concerns the gene RBKS and type 2 diabetes mellitus.