In Discovery Dataset (TCGA‐STAD), we investigated the expression pattern of eight immune‐checkpoint‐associated genes in gastric cancer: VSIR (VISTA),26HAVCR2 (TIM‐3),27TIGIT (TIGIT),28KLRC1 (NKG2A),29CD274 (PD‐L1),30LAG3 (LAG‐3),31CTLA4 (CTLA‐4)4 and PDCD1 (PD‐1),32 which were previously reported to be promising targets for immunotherapy. This evidence concerns the gene CD274 and gastric cancer.