Pimozide promoted the degradation of ID1 mediated by USP1, which led to interference in cancer progression.52 Reports had shown that ID1 could activate the RAF/MEK signaling pathway in nasopharyngeal carcinoma cells and glioblastoma,53,54 which might reveal that ID1 had a similar effect in breast cancer cells. Here, USP1 is linked to glioblastoma.