TP53 and Mobius syndrome: Garancher et al. indicated that the failure of MG MBs (co-expression of Myc and Gfi1) to grow in immunocompetent mice was due to rejection by T cells, whereas tumor necrosis factor could overcome immune evasion in p53-mutant MP MBs (overexpression of Myc and dominant-negative Trp53) [117].