Furthermore, in a report examining immunosuppressive therapy and its impact on the severity and outcome in patients diagnosed with SARS-CoV-2, exposure to selective immunosuppressive agents, tumor necrosis factor inhibitors, interleukin inhibitors, calcineurin inhibitors, other immunosuppressive agents, hydroxychloroquine, and chloroquine were not associated with COVID-19 severity; however, exposure to glucocorticoids has been reported to be associated with an increased risk of hospitalization and death21–23. This evidence concerns the gene TNF and COVID-19.