Because the IL-6 level in 4T1 BMDMs was higher than IL-23, and Il-6 gene was the most induced interleukin in 100 IU + cal group treated both with 4T1 CM and 4T1cal CM, we checked its secretion to supernatants and compared it with previously published results of IL-6 concentration in tumor tissue homogenates from 4T1 tumor-bearing mice32. This evidence concerns the gene IL6 and neoplasm.