Moreover, tumor tissue homogenates showed a similar trend in IL-6 concentration for 100 IU + cal (554 ± 176 pg/mg) compared with 1000 IU (403 ± 94 pg/mg) and 100 IU (315 ± 33 pg/mg) treated mice (data in pg/mg of tumor tissue; P = 0.0869 and P = 0.0124, respectively, Sidak’s multiple comparison test, data presented in the supplementary file of our previous paper32). This evidence concerns the gene IL6 and neoplasm.