Cells from each patient were represented across all clusters (Fig. 1G) and expression of the RUNX1T1 (ETO) transcript was detected in 6711/14485 cells (Fig. 1H) distributed across all clusters, thereby confirming that all cell clusters comprised AML or pre-leukemic cells as RUNX1T1 is not expressed in healthy myeloid cells23. Here, RUNX1T1 is linked to acute myeloid leukemia.