Univariate logistic regression analysis revealed that age, sex, BMI, operation time, intraoperative blood loss, history of hypertension, history of diabetes, history of cerebrovascular disease, history of osteoporosis, TP, ALB, SAA, RBC, HB, HCT, and MCHC were associated with postoperative anemia in this cohort. The gene discussed is ALB; the disease is Hypertension.