DM on insulin, BMI (kg/m2) > 30, absolute BMI (kg/m2), PAD, eGFR, eGFR < 50 ml/min, preoperative hospital stay ˃ 24 h, re-exploration for bleeding, BIMA harvesting, AKI and blood transfusion rounded independent variable set for postoperative “Improved Baseline” model (Table 3 and Supplementary Tables 3 - Additional File). The gene discussed is INS; the disease is peripheral arterial disease.