Among the nine key cuproptosis-related lncRNAs we obtained, MME-AS1 has been confirmed to be related to the survival in intrahepatic cholangiocarcinoma [34], while OTUD6B-AS1 is not only associated the progression of various cancers, but also with tumor drugs resistance [35–37]. The gene discussed is MME; the disease is intrahepatic cholangiocarcinoma.