Remarkably, when examined separately within non-AD cases (Braak stage 0-IV) and AD cases (Braak V–VI), correlations between AT-8 phospho-tau and Aβ were apparent in both control (GM; r = 0.61, p < 0.0001 and WM; r = 0.66, p < 0.0001, Fig. 1d.ii + e.ii) as well as AD cases (r = 0.5, p < 0.05 and r = 0.73, p < 0.001 in GM and WM, Fig. 1 d.iii + e.iii). Here, MAPT is linked to Alzheimer disease.