MAPT and Alzheimer disease: When controlling for age, no significant correlations were observed for AT-8 phospho-tau for either non-AD (Braak stage 0–IV) or AD (Braak stage V–VI) groups (p > 0.05), although a modest correlation of Aβ plaque load with Braak NFT stage was observed in non-AD controls (Braak 0–IV; r = 0.35, p < 0.05, Fig. 2c.ii).