SLC17A1 and cancer: As a functional component of system Xc-, which imports extracellular cystine with intracellular glutamate release at a ratio of 1:1, solute carrier family 7 member 11 (SLC7A11, also known as xCT) acts as an oncogene against oxidative stress and ferroptosis and affects cancer phenotypes and the immune system (Lin et al. 2020b).