As a functional component of system Xc-, which imports extracellular cystine with intracellular glutamate release at a ratio of 1:1, solute carrier family 7 member 11 (SLC7A11, also known as xCT) acts as an oncogene against oxidative stress and ferroptosis and affects cancer phenotypes and the immune system (Lin et al. 2020b). Here, SLC7A11 is linked to cancer.