In SCLC cells, the expressions of RAB27A and nsMase2, CD63, CD9 and TSG101 were significantly reduced in all treatment groups when compared to the control (*p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001) (Figure 2). The gene discussed is CD63; the disease is small cell lung carcinoma.