To further explore the association between PANK4 expression and TMZ resistance, we used the Gene Expression Omnibus database (GEO; accession number: GSE68029) and examined kinases that were previously reported to be differentially expressed in TMZ‐resistant and parental GBM stem cells (GSCs).[28, 29] Intriguingly, PANK4 was found to be upregulated in the TMZ‐resistant group compared with parental cells that were sensitive to the drug. The gene discussed is PANK4; the disease is glioblastoma.