TBX20 encodes the T-box transcription factor 20 protein, which is a member of the T-box superfamily that is highly expressed in embryonic heart tissues.5,6 Genetic variants in TBX20 have been linked with CHD, and a potential association between variants in TBX20 and the development of DCM in the absence of CHD has been proposed7; however, this association has not yet been definitively established. The gene discussed is TBX20; the disease is familial dilated cardiomyopathy.