DSP and central nervous system cancer: In line with the KM analysis of pan-cancer, the KM analysis or univariate Cox regression in individual cancer type indicated that the 3 DSP clusters could serve as a significant survival-related factor in colon adenocarcinoma (COAD), CRCA [COAD + rectum adenocarcinoma (READ)], glioblastoma multiforme (GBM), glioma, head and neck squamous cell carcinoma (HNSC), kidney chromophobe (KICH), kidney renal clear cell carcinoma (KIRC), lung adenocarcinoma (LUAD), lung carcinoma (LCA), stomach adenocarcinoma (STAD), uterine corpus endometrial carcinoma (UCEC), and uveal melanoma (UVM) (Figures 5G–I).