Ten hub genes (IL2RB, CD96, CD3D, HOXC9, HOXC5, SLAMF6, GZMH, CD3E, GZMK, and GZMA) from this module were screened by cytoHubba to construct an enhanced refined DSP clustering model by ML in glioma (Figure 9H). Here, HOXC5 is linked to central nervous system cancer.