TGFB1 and rheumatoid arthritis: The results indicated that curcumin could specifically reduce the differentiation of Th17 cells in CD4+T cells of patients with RA in vitro and promote their differentiation into Treg cells, and regulate the function of Th17 and Treg cells and the balance of Th17/Treg cells by reducing IL-17 and increasing TGF-β.