To assess the dynamics of immune cells at different stages of acute and chronic infections, CD45+ immune cells from the lymph nodes of mice with acute LCMV Armstrong (Arm) infection or chronic LCMV clone 13 (Cl13) infection at 0 (Naive), 4, 8 and 30 days post-infection (dpi) were isolated by fluorescence-activated cell sorting (FACS) and subjected to scRNA-seq or TCR/BCR sequencing (Figure 1A). Here, PTPRC is linked to infection.