Immunoprecipitation studies in HA-CHMP5-expressing T-ALL cells showed p300 association with CHMP5 in nuclear lysates from CUTLL1 T-ALL cells (Figure S4B) and in cell-free assays, recombinant CHMP5 immunoprecipitated with p300 (Figure 4D), consistent with a direct binding between both proteins. Here, CHMP5 is linked to acute lymphoblastic leukemia.