We confirmed this CHMP5-BRD4 interaction in independent reverse immunoprecipitation of endogenous BRD4 in nuclear lysates from human T-ALL cell lines (CUTLL1 and Loucy), primary PDX human T-ALL (Figures 2E, 2F and S2E), and in HEK293T cells co-transfected with plasmids encoding these proteins (Figure S2F). Here, CHMP5 is linked to acute lymphoblastic leukemia.