TG and hypothyroidism: While many individuals are asymptomatic, some may exhibit evidence of disrupted thyroid hormone levels or nerve involvement. Symptoms of hyperthyroidism include nervousness, heat intolerance, diarrhea, muscle weakness, and loss of weight and appetite. Hypothyroidism may result in cold intolerance, constipation, fatigue, and weight gain, which, in children, is primarily caused by the accumulation of myxedematous fluid. Prompt investigation is warranted when signs and symptoms of local nerve involvement arise, as they could signify potential malignancy-related local invasiveness.