Mowat-Wilson syndrome (MOWS; OMIM #235730) is a rare neurodevelopmental disorder (NDD) caused by heterozygous deletions or loss-of-function (LoF) variants of the ZEB2 gene (HGNC:14881; locus 2q22.3) [1, 2]. This evidence concerns the gene ZEB2 and Mowat-Wilson syndrome.