For example, NSUN2-mediated aberrant m5C modification of lncRNA H19 is closely related to poor differentiation of HCC, and H19 lncRNA can specifically bind to the oncoprotein ras-GTPase-activating protein binding protein 1 (G3BP1) to further lead to MYC accumulation [32]. The gene discussed is NSUN2; the disease is hepatocellular carcinoma.