The top locus was (rs12929564 G/A; OR = 1.67; p = 2e-6) in an intronic region of RBFOX1. In the PGS analysis, a higher PGS for antidepressant response in MDD was associated with higher odds of TEM in BD (OR = 1.16 per SD increase in the PGS; p = 0.047). The gene discussed is RBFOX1; the disease is major depressive disorder.