Unexpectedly, small differences in the frequencies of the 2 T cell subsets remained between Gpr43−/−-Dub and Gpr43−/−-Veh groups, whereas no differences were observed between Gpr43−/−-Prop or Gpr43−/−-Veh groups (Fig. 3h, i and Supplementary Fig. 6d), indicating a full involvement for GPR43 in the propionate-mediated Treg/Th17 rebalancing in the context of DSS-induced colitis. Here, FFAR2 is linked to colitis.