CCR7 and neoplasm: Subsequently, TCR-T cells underwent single or repeated stimulation with HepG2 tumor cells in the presence of ATO, and we assessed the proportional changes among various T-cell subsets, including naïve T cells (TN; CD45RA+CCR7+), central memory T cells (TCM; CD45RA−CCR7+), effector memory T cells (TEM; CD45RA−CCR7−) and CD45RA+ effector memory cells (TTEMRA; CD45RA+CCR7−).